What antivirus program the best to use for Mac

No Anti-Virus software or so-called “cleaning” apps are needed or recommended for Mac OS. They can conflict with Mac's own built-in security. At best they will slow your Mac by using unnecessary resources and at worst will bork your entire system. Your Mac has all the built-in protection you need.

macOS - Security - Apple

If you suspect malware then download and run Malwarebytes. Malwarebytes was developed by one of our own colleagues here in ASC and is about the most proven anti-malware software for Mac.

VitaliyfromWA wrote:

What antivirus program do I have to use for my Mac OS High Sierra

It's called macOS High Sierra.

The only improvement as of this writing would be macOS Mojave.

Effective defenses against malware and other threats

Avoid so-called "cleaners", "doctors" etc. That goes double for any "doctor cleaners".

Effective defenses against malware and ot… - Apple Community

Use your brain. Most efficient and least obtrusive. See Bob's link to fine tune the programming.

Only if you must...

Malwarebytes...

https://www.malwarebytes.com/mac/

You can try Dr. Antivirus if you trust me, just download from the Appstore.