Can I sync my iTunes with my iPhone wirelessly?

Yes.

Turn on Wi-Fi syncing. Connect your device to your computer. In the iTunes app on your PC, click the Device button near the top left of the iTunes window. --> Sync iTunes content on PC with devices on Wi-Fi - Apple ...

To set up wireless sync you must first sync with a cable. After the first cable sync you can enable Wi-Fi sync. There’s a checkbox in iTunes to enable it. If you don’t see the phone make sure you have the latest version of iTunes from https://apple.com/itunes as the version from Microsoft does not include iPhone drivers.

Here’s more help on connecting—>If your computer doesn't recognize your iPhone, iPad, or iPod - Apple Support

The instructions to do that are in the link provided by SravanKrA. If you are not familiar with links, a link on a web page opens a new page with additional information. Usually links have blue text, and you click anywhere on the blue text to open the new page.

You need to connect the phone and look in iTunes (Finder if you have a Mac with Catalina) for the iPhone icon at the top. Clic on it and a Summary page will open. The checkbox for Wi-Fi sync is on the Summary page. It is not on your iPhone. I don’t know why you were looking in Settings/General On the phone when the link does not mention that at all.

You must connect the phone to the computer with a lightning to USB cable. It should then appear in iTunes.