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Does endnote work with the new M1 MacBooks?

I would like to buy a new MacBook but for uni I need it to be able to run ChemDraw and Endnote, does anyone know if the new M1 chip is compatible with this software?

Posted on Dec 13, 2020 3:58 AM

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Question marked as Top-ranking reply

Posted on Jan 2, 2021 6:59 PM

Both Endnote and ChemDraw work on the M1 Mac but not natively. They run on the Rosetta 2 system. However, you won't notice much of a difference as these softwares run super fast on this M1 chip even when they don't run natively. There would only be one slight glitch as there is a new M1 compatible version of MS Word. If you have this version automatically installed on Mac, then it would not recognize your Endnote due to the mismatch with the "cite while you write" compatibility. The trick to get around this is as following:

  1. Quit EndNote and Word.
  2.  Open Finder and go to the Applications folder. 
  3. Highlight the Microsoft Word app file by clicking on it once. Note: You do not need to launch Word, just highlight it.
  4. Go to the File menu at the top of your screen and choose Get Info.
  5. Under General, check the option for Open using Rosetta.

This is a temporary solution to the issue and won't be resolved fully until Endnote releases a software update compatible to run natively on the M1 chip.

Hope this helps.


6 replies
Question marked as Top-ranking reply

Jan 2, 2021 6:59 PM in response to luc3b99

Both Endnote and ChemDraw work on the M1 Mac but not natively. They run on the Rosetta 2 system. However, you won't notice much of a difference as these softwares run super fast on this M1 chip even when they don't run natively. There would only be one slight glitch as there is a new M1 compatible version of MS Word. If you have this version automatically installed on Mac, then it would not recognize your Endnote due to the mismatch with the "cite while you write" compatibility. The trick to get around this is as following:

  1. Quit EndNote and Word.
  2.  Open Finder and go to the Applications folder. 
  3. Highlight the Microsoft Word app file by clicking on it once. Note: You do not need to launch Word, just highlight it.
  4. Go to the File menu at the top of your screen and choose Get Info.
  5. Under General, check the option for Open using Rosetta.

This is a temporary solution to the issue and won't be resolved fully until Endnote releases a software update compatible to run natively on the M1 chip.

Hope this helps.


Does endnote work with the new M1 MacBooks?

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