iMac OS X 12.1 (Monterey)
Is My WD My Passport for Mac compatible with OS X 12.1?
iMac 27″ 5K, macOS 12.1
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Yes the external hard drive should work with your iMac for backup or file storage.
However, the WD software that should be avoided might not be compatible.
If you are having issues with the WD external drive, then you need to provide more specific information.