Hardrive transfer
What cable is best for transferring hardrive from my 2012 21.5 imac with no screen to my new Mac studio .thank you
iMac
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Migration to a new Mac:
Move content to a new Mac - Apple Support
Since Migration Assistant 'takes over' both computers, you will want to set this up late in the day and let it run overnight, and be ready for it not to be done by morning.
"the best way" is to use your Time machine backup from the old Mac as the source for Migration Assistant running on the new Mac. USB-2 is as fast as almost every Rotating Magnetic drive, and will not produce a noticeable slowdown doing this transfer.
The way that always works but is dog-slow is using Wi-Fi through your Router.
If you could use Ethernet through your Router to BOTH Macs, that would be much faster. OR, if your old Mac is running 10.12 Sierra or later it can establish an Ad-hoc private Wi-fi connection to the new Mac when placed near the new Mac and both running Migration Assistant.
If you old Mac has no Thunderbolt-3 ports, direct Thunderbolt Bridge is off the table.
A USB cord sounds like a great idea, but does not work because USB is a local peripheral interface, and a Network interface is required, unless you can make your old Mac "look like a drive' to the new Mac.
Target Disk Mode can allow your old Mac to become a Hard drive, and it can be cable-connected to the new Mac. It requires ThunderBolt cable connection, so you would need to obtain a Thunderbolt-3 <-> thunderBolt-2 adapter (US$50) and a Thunderbolt-2 cable.
Transfer files between two Mac computers using target disk mode - Apple Support