...and further to my last comment earlier today (30 March)...the screen (Apple Thunderbolt) went black while working with MBP lid closed and two external displays, but TimeMachine was backing up so I didn't want to reboot. I was typing a LinkedIn message at the time in the main screen (which is the one that went black); finished typing the message even though I couldn't see the LinkedIn screen, hit enter, and the message was completed (though not visible). I opened the lid, the screens reconfigured, with the main display still black. I deleted the cache files, but there was no change; kept working anyway on the MBP display and the external LG display. I then went to watch TV for a couple of hours to let TimeMachine finish. Came back and the main display was working again...!!! The things that were different since the screen went black were: caches deleted; MBP lid still open; TimeMachine had finished its backup. I still think this is a software problem, given that it didn't start until upgrade to Sequoia and the fact that the problem always clears on a reboot. BTW, I checked the boot time (thinking that the MBP had rebooted itself while I was watching TV), but the System Report/ Software says: "Time since boot: 2 days, 3 hours, 22 minutes" - so, no, it didn't reboot while I was gone. What's happening...???