I suggest that you start by reviewing the M4 Mac Studio's display specs. The following is taken directly from the Apple Specifications for this model.
Display Support
Apple M4 Max chip
- Simultaneous support for up to five displays:
- Up to four displays with 6K resolution at 60Hz over Thunderbolt and one display with 4K resolution at 144Hz over HDMI
- Up to two displays with 6K resolution at 60Hz over Thunderbolt and one display with 8K resolution at 60Hz or 4K resolution at up to 240Hz over HDMI
The Macs HDMI port support the HDMI 2.1 protocol; its DisplayPort support the DisplayPort 2.1 protocol.
As you can see the Mac is very capable.
Similarly, the specs for your Eizo monitor will need to be reviewed to see which ports will provide you with the best possible connection between these two devices.
Some things to consider:
- macOS is optimized for Retina scaling, meaning it looks best when UI elements are rendered at 2x scale (e.g., rendering a 5120x2880 workspace downsampled to a 2560x1440 display). Since the CS2731 is 2560x1440 native, macOS will, by default, render at 1:1 without scaling (which can make UI elements look small), or it might try to scale UI elements to appear like 1920x1080, which introduces blur. As you mentioned, that’s where tools like BetterDisplay come in—they let you define custom scaling modes and render at 5K or 4K, then downscale to 1440p, creating a pseudo-Retina effect.
- If text sharpness and UI clarity are a top priority for you and you’re used to Retina screens (like the ones on MacBook Pros or the Studio Display), you may eventually feel limited by 1440p’s physical pixel density. The Apple Studio Display (5K at 27") truly shines with 2x scaling (looks like 2560x1440), giving you perfect sharpness and ideal UI size.
With all that said, and with the Eizo display, I would suggest that you consider using DisplayPort over USB-C (Thunderbolt 4) is your best bet for maximum clarity and native resolution support, particularly for high color accuracy and full bit depth.