iTunes Won't Open After Windows 10 Update

If you uninstalled iTunes, did you uninstall iTunes and related Apple components? There are 6 in all. I would recommend you uninstall them in order. Refer to the following article for specific order. hthttps://support.apple.com/en-us/HT204275

Then go to the Microsoft Store to redownload iTunes.

For general advice see Troubleshooting issues with iTunes for Windows updates.

The steps in the second box are a guide to removing everything related to iTunes and then rebuilding it which is often a good starting point unless the symptoms indicate a more specific approach. When reinstalling right click on the downloaded setup file and use run as administrator. It may also help to temporarily disable any non-Microsoft anti-virus.

Review the other boxes and the list of support documents further down the page in case one of them applies.

The further information area has direct links to the current and recent builds in case you have problems downloading, or want to revert to an older version if the current one won't work properly for you at the moment. Links to the most recent builds are now at the bottom of the page.

Your library and device backups should be unaffected by these steps but there are links to backup and recovery advice should it be needed.

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If you have problems accessing the Microsoft Store use the traditional installer instead. As noted above:

The further information area has direct links to the current and recent builds in case you have problems downloading, or want to revert to an older version if the current one won't work properly for you at the moment. Links to the most recent builds are now at the bottom of the page.

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Try installing a newer version of iTunes.

Even when you uninstall iTunes, the original setup file is still located on your PC. Do a search in file explorer or through Cortana...type in iTunes. That should bring up the original setup file.