Install and Un-Install
the fundamental principles:
• anything installed with drag-and-drop to the /Applications folder can be un-installed by Drag-and-drop to the Trash. After a restart, the Trash can be emptied.
• anything installed with a complex installer program requires the manufacturer's un-installer program. sometimes this is included as an "option" in the Installer package, but the software-maker's web site should specify how to un-install (if they don't, they get swamped with users clamoring for Un-install Instructions).
DO NOT use any other web site’s instructions, unless you have complete trust in that specific site to tell you the truth.
Third-party un-installers could be malicious. The Classic case is malicious updaters for Flash Player.
• anything claiming to be an 'uninstaller helper' is just JUNK. (worse than web site click-bait)
Remember that you can not immediately DELETE anything hat is part of the running MacOS, because if it were referenced after being deleted, your Mac would crash. What you can often do is Move to Trash, and after a Restart, the item will no longer be part of the running MacOS and the Trash can be emptied.
MANY user find that CleanMyMac is one of the worst. it has a reputation for discarding far more than is appropriate, and sometimes after using it, the only way to recover is the re-Install macOS.