Then I would recommend running DriveDx (free trial period) as suggest by some of the others to check the health of that drive. Post the complete DriveDx text report here using the "Additional Text" icon which looks like a piece of paper on the forum editing toolbar. You will need to install a special USB driver in order to access the health information on the external drive. Even new drives can be bad.
I know a couple of people have reported resolving recent external drive issues by connecting the drive to a USB3 hub instead of connecting the drive directly to the computer. I would also recommend disconnecting all other external devices while troubleshooting just in case one of them is causing a problem.
Also make sure to try using a different high quality USB-C USB3/4 cable (or Thunderbolt 3/4) cable from a well respected manufacturer. Many people resolve external drive issues by using higher quality cables from respected manufacturers. Same thing goes if you need to use any adapters. The cables supplied by the drive manufacturers are usually of poor quality.
And of course try each other USB-C port on the Mac.